Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep251 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Canagliflozin and liraglutide effect on myocardial damage in diabetic rats with experimental myocardial infarction

Timkina Natalya , Simanenkova Anna , Shimshilashvili Anzhelika , Timofeeva Valeria , Chernikova Alena , Minasian Sarkis , Galagudza Michael

Background: Cardiovascular events are the major cause of mortality among patients with type 2 diabetes mellitus (DM2). Menopause in women additionally increases cardiovascular risk. Despite myocardial infarction (MI) treatment approach in diabetic patients is not specific, some glucose-lowering drugs could have cardioprotective properties. In general, most glucagon-like peptide-1 receptor agonists (GLP-1Ra) and sodium-glucose co-transporter-2 inhibitors (SGLT-2i) have cardiova...

ea0073oc12.3 | Oral Communications 12: Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Comparative evaluation of empagliflozin, canagliflozin and sitagliptin cardioprotective effect in diabetic rats with experimental myocardial infarction

Simanenkova Anna , Minasian Sarkis , Karonova Tatiana , Vlasov Timur , Timkina Natalya , Khalzova Aleksandra , Shpilevaya Oksana , Shimshilashvili Anzhelika , Timofeeva Valeria , Borshchev Yury , Galagudza Mikhail

Background:Myocardial infarction (MI) is one of the leading causes of mortality in patients with type 2 diabetes mellitus (DM), therefore it is essential to give preference to a glucose-lowering drug having most prominent cardioprotective properties. Sodium-glucose co-transporter-2 inhibitors (SGLT-2i) have demonstrated an ability to decrease heart failure manifestations, cardiovascular death frequency not having a certain influence on MI occurrence. On ...